From Yahoo News
This is a practice so prevalent and accepted. From an economic standpoint, it is usually cheaper to buy a higher dose pill and split it rather than to get a lower dose pill. It is like a promotional pitch of “buy one and get another at half the price”.
Just by thinking about it, one can deduce that the pill splitting act will reduce the accuracy of the dose taken. Not only does the pill fragment but tiny bits will stick to the knife or pill cutter that is used.
Does the minute changes in dose matter more than the economic burden that most patients face?